How We Engage
Two engagement models — chosen based on the structure the moment requires.
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Fractional C-Suite Leadership
Embedded executive leadership without a full-time hire.
Fractional CCO, CBO, or CMO engagements for life sciences companies that need senior commercial firepower for a defined period — typically multi-quarter, with direct accountability to the board and integration into executive team rhythm.
Strategic Advisory & Project Work
Defined-scope engagements for specific inflection points.
Project-based engagements organized around a single primary objective, with additional workstreams scoped and authorized as the work evolves. Standard rate is $250/hour; engagements are scoped against a primary goal with workstreams defined for the initial committed scope.
What We Do
Six capabilities that show up across both engagement models.
Capital Formation & Investor Relations
Seed through Series C support, convertible note bridges, capital structure narratives, board and investor communications, and the alignment of commercial strategy with funding milestones. Active experience leading capital raises and presenting directly to investor stakeholders.
Business Development, In-Licensing & Partnerships
Diligence, term sheet development, partnership structuring, and partner identification. Active experience leading in-licensing negotiations for specialty therapies and structuring strategic partnerships across the life sciences ecosystem.
Commercial Strategy & Launch Readiness
Brand strategy, sales force design, launch planning, and commercial team scale-up. Built on 15+ product launches across neurology, oncology, cardiology, women’s health, urology, infectious disease, dermatology, and rare disease.
Market Access, Pricing & Commercialization
Payer strategy, specialty pharmacy, managed care contracting, distribution, and pricing model design. Deep functional experience built across senior roles at Teva, Bayer, Veru, and Evofem.
Board & Investor Communications
Strategy updates, financial performance reporting, pipeline development briefings, and the capital narrative work that connects board discussions to investor confidence.
Leadership Advisory
Senior advisory support for executive teams facing high-stakes commercial decisions — sounding board, strategic counsel, and frameworks for the moments where outside perspective from someone who has done it before changes the answer.
How an ISG Engagement Works
Every engagement follows a consistent process — calibrated to the engagement model and the inflection point at hand.
Diagnostic Conversation
We define the inflection point, success criteria, and the leadership structure that fits the moment. Typically a 30–60 minute conversation, no obligation.
Engagement Design
We propose the engagement structure (fractional or project) and scope the primary engagement, including any additional workstreams that may be authorized as work evolves.
Strategic Work
We deliver the substantive engagement: commercial strategy, capital formation, BD/in-licensing, launch planning, or whatever the moment demands.
Board & Investor Engagement
For most engagements, we present directly to boards of directors and investor stakeholders — providing commercial strategy updates, financial performance reporting, and pipeline development briefings.
Outcome & Transition
We close out engagements with clear deliverables and structured transition to internal leadership where appropriate.
Why Life Sciences Companies Engage ISG
Five things ISG brings that most life sciences advisors don’t.
01
Senior Bench
Engagements are led by someone with 30 years of senior commercial leadership across pharma, biotech, medical devices, and diagnostics — not associates, not project managers.
02
Strategic Architect AND Operational Executor
Most advisors do strategy or execution. ISG does both — often inside the same engagement. Capital narratives that survive contact with execution. Strategies built by people who will help build the team to execute on them.
03
Engagement Models That Fit the Moment
Fractional or project-based, calibrated to what the inflection point actually requires. No forcing the moment into a fixed deliverable structure.
04
Direct Investor & Board Experience
Active experience presenting to boards of directors, leading investor conversations, and translating commercial performance into capital narratives — across multiple companies, multiple financing rounds.
05
Life Sciences Specialty
30 years inside life sciences. Not generalist consulting applied to life sciences — life sciences depth applied to commercial leadership.
Ready to Define the Engagement?
Every engagement starts with a diagnostic conversation. Let’s talk about what you’re facing and the structure that fits the moment.