Capital Formation Built on Fundable Commercial Stories

Senior commercial leadership for the capital decisions that determine whether life sciences innovation reaches the patients who need it. Built on direct experience leading $100M+ across public and private market raises, including reverse merger transactions, with active board and investor engagement across early- and growth-stage life sciences companies.

$100M+

Capital raised

Public + Private

Including reverse merger

Active

Fractional CCO engagement

Fundable, Investor-Ready Commercial Stories

Capital flows to companies that tell credible commercial stories backed by data — and that tell them consistently across rounds. ISG works at the intersection of commercial strategy and financial planning, building the integrated narratives, models, and data packages that get rounds closed and hold up under investor diligence.

We don’t produce decks. We build the underlying commercial logic — what the market looks like, what the company is going to do in it, when the value gets created, and what each capital event is buying — and then translate that logic into the materials investors actually need to commit.

  • Investor relations strategy and engagement rhythm
  • Pitch preparation, modeling, and investor materials
  • Milestone-based capital allocation aligned to commercial inflection points
  • Data packages designed to support each successive funding event
  • Commercial strategy and financial planning, integrated to reduce investor risk
  • Board and investor communications across the round and post-close
Book Strategy Call

Outcomes That Compound Across Rounds

Capital formation work at ISG is structured to maximize enterprise value at every funding event — and to make the next round easier to close than the last.

OUTCOME

Capital Aligned to Commercial Strategy

Round structure, sizing, and milestone definition that map directly to the commercial inflection points the capital is meant to fund. Capital that buys the right things, in the right sequence, at the right cost.

OUTCOME

Investor Confidence That Holds Across Rounds

Commercial narratives built to survive contact with execution and to compound credibility across successive raises. The story you tell investors at Series A becomes the foundation of the Series B story — not a contradiction of it.

OUTCOME

Round Close Discipline

Diligence-ready data packages, financial models, and commercial materials that anticipate investor questions before they’re asked — compressing the close cycle and protecting valuation.

OUTCOME

Board-Level Commercial Fluency

Direct engagement with boards and investor stakeholders, translating commercial performance into capital narratives and providing the senior commercial fluency that materially affects financing outcomes.

How We Approach Capital Formation

Methodology built on direct experience leading capital raises across public and private markets in life sciences — informed by the operational reality of building and running the commercial organizations the capital is meant to fund.

01

Capital Diagnostic

Map current cash, runway, and the commercial milestones the next round must fund. Identify the gap between what the company has and what the next inflection point requires.

02

Capital Narrative Development

Build the integrated commercial-financial narrative: market opportunity, commercial strategy, milestone economics, and the specific value each capital event creates.

03

Data Package Build

Produce diligence-ready commercial and financial materials: market models, forecast logic, commercial assumptions, competitive landscape, and the supporting evidence base.

04

Investor Engagement

Lead or support pitch preparation, investor meetings, modeling work, and the IR rhythm during the active round.

05

Round Close & Post-Close Communications

Close out the round and establish the post-close board and IR communication cadence that sets up the next raise.

Where Capital Formation Engagements Concentrate

Core strategic pillars that drive successful commercialization and long-term market success.

  • Investor Relations Strategy
    • IR cadence design and execution
    • Investor targeting and engagement strategy
    • Quarterly and milestone communications
  • Pitch Preparation & Modeling
    • Investor pitch deck development and refinement
    • Financial model build and stress-testing
    • Q&A preparation and rehearsal
  • Market Insights & Forecasting
    • Market sizing and addressable opportunity
    • Commercial forecasting and assumption logic
    • Competitive intelligence and landscape analysis
  • Milestone-Based Capital Allocation
    • Round sizing aligned to commercial milestones
    • Capital allocation across functions
    • Bridge financing and convertible note structuring
  • Public Market Pathways
    • Reverse merger evaluation and execution
    • Public market readiness assessment
    • Public-private capital structure transitions
  • Board & Investor Communications
    • Board-level commercial reporting
    • Strategy updates and pipeline development briefings
    • Investor stakeholder management

Companies This Engagement Is Built For

Pre-Commercial Biotech

Companies preparing for or executing seed through Series C raises that need senior commercial leadership integrated into the capital story.

Early-Stage Medical Device Companies

Companies preparing for capital raises where commercial credibility is the binding constraint on valuation and round size.

Companies Evaluating Public Market Pathways

Companies considering reverse mergers, secondary offerings, or other public market transitions where commercial narrative and IR infrastructure are critical.